Senior Scientist, Biomarker Laboratory, Pathology

Company: BeiGene, Ltd.
Location: San Carlos
Posted on: May 24, 2025

Job Description:

Senior Scientist, Biomarker Laboratory, Pathology
Apply locations San Carlos
Time type: Full time
Posted on: Posted 3 Days Ago
Requisition ID: R28987
BeiGene, Ltd. has proposed to change its name to BeOne Medicines Ltd. The new name is subject to shareholder approval and, once approved, use of the name will be phased in over 2025. During this transition, "BeiGene" or "BeOne" may be used to describe the company. BeOne continues to grow rapidly, offering challenging opportunities for experienced professionals who are highly motivated, collaborative, and passionate about fighting cancer.
General Description:
We are seeking a highly motivated and detail-oriented Senior Scientist to lead the development, validation, and execution of immunohistopathology (IHC) assays in a clinical biomarker setting. The successful candidate will support clinical trials and translational research by generating high-quality, tissue-based biomarker data. This role involves collaboration with pathologists, clinical teams, and CDx development functions to ensure assays are robust, reliable, and fit-for-purpose for oncology and non-oncology pipelines.
Essential Functions of the job:

• Lead strategic design and implementation of the new IHC workflow.
  
• Design, develop, and optimize IHC assays for biomarker detection in fresh and FFPE tissue samples.
  
• Select and validate antibodies, detection systems, and staining protocols to ensure assay specificity and sensitivity.
  
• Validate IHC-based assays and analyze clinical samples. Oversee IHC staining and imaging; coordinate with pathologists for interpretation and scoring.
  
• Author and review method development and validation protocols, reports, and SOPs.
  
• Ensure quality control, data integrity, and timely delivery of results.
  
• Contribute to cross-functional project teams supporting clinical trial biomarker strategies.
  
• Maintain accurate lab records and mentor junior scientists.
  
  Supervisory Responsibilities:
  This role is initially an individual contributor but may supervise lab scientists as the team expands.
  Computer Skills:
  Proficiency in Microsoft Office (Word, Excel, PowerPoint), Outlook, Zoom, Teams, and IHC-related systems.
  Other Qualifications:
  

• 
  
• Ph.D. with 2+ years or M.S. with 4+ years of hands-on IHC assay experience in a clinical or regulated environment.
  
• Strong background in IHC assay development and validation using fresh or FFPE tissues.
  
• Familiarity with automated staining platforms (e.g., Ventana, Leica, Dako) and image analysis software (e.g., HALO, QuPath).
  
• Understanding of clinical biomarker strategies and regulatory requirements.
  
• Analytical and problem-solving skills, critical thinking.
  
• Excellent communication, organization, and project management skills.
  
• Experience with lab automation, ELN, LIMS, and lab workflow setup is a plus.
  
  Education Required:
  PhD in Pathology, Molecular Biology, Immunology, or related field with 2+ years of relevant experience, or MS with 4+ years.
  Travel:
  Under 10%
  Global Competencies:
  We value global competencies such as teamwork, feedback, self-awareness, inclusivity, initiative, entrepreneurial mindset, continuous learning, adaptability, results orientation, data analysis, financial excellence, and clear communication.
  Salary Range: $118,000 - $158,000 annually
  BeiGene is committed to fair, equitable compensation practices. Actual packages depend on skills, experience, education, and location. Benefits include medical, dental, vision, 401(k), FSA/HSA, life insurance, paid time off, wellness, and opportunity for equity participation.
  We are an equal opportunity employer valuing diversity. We do not discriminate based on race, religion, gender, age, disability, or other protected categories. Employment decisions are based on qualifications, merit, and business needs.
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Keywords: BeiGene, Ltd., Newark , Senior Scientist, Biomarker Laboratory, Pathology, Healthcare , San Carlos, California